Our Therapy Areas

Our dream to develop novel and targeted medicines for every patient who needs them is becoming a reality. The future treatment for many diseases today lies in uncovering mechanisms that are newly emerging or are yet to be discovered. Focusing on breakthrough science in Oncology; Cardiovascular, Renal, & Metabolism; and Respiratory & Immunology, our ambition is to transform the lives of patients with improved outcomes and a better quality of life through prevention and more effective treatments. Ultimately, we are working toward finding cures for some of the most complex diseases in the world.

Oncology

Our scientists work every day to turn science-fiction into reality by using a four-front offense to cancer – 1) Immuno-Oncology: Using the body’s immune system to help fight cancer; 2) Antibody-Drug Conjugates: Arming antibodies with cancer-killing agents for specific tumor targeting; 3) DNA Damage Response: Targeting the DNA repair process to block tumor cells ability to reproduce; and 4) Tumor Drivers and Resistance: Developing therapies that target specific mutations to attack cancer cells.

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Cardiovascular, Renal, & Metabolism

We are following the science to develop novel innovative treatments to slow the progression of Cardiovascular, Renal, & Metabolism (CVRM) diseases. Using data from real-world settings to evaluate their connection, we are redefining how they are understood, interact, and impact one another. In the not too distant future, we hope to halt the course of CVRM diseases and have organs regenerate.

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Respiratory & Immunology

We are striving to find a cure for patients with respiratory diseases by focusing on four complementary approaches – 1) Lung Epithelium: Identifying new drug targets that can change the course of inflammatory disease; 2) Lung Immunity: Restoring a healthy balance in the immune system by immunomodulation, improved cell metabolism, and battling bacteria/viruses in the lungs; 3) Lung Regeneration: Repairing lung damage by stimulating the regrowth of lung cell tissue; and 4) Neuronal Functions: Recognizing the role that inadvertent coughing plays as a neuronal reflex, which can dramatically impact the quality of life for patients.

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What Transformative Science Can Do

Turning science into medicine, we are always searching for new knowledge and the next breakthrough.
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